大鼠背部穿支体区间choke血管变化规律初探

doi:10.13418/j.issn.1001-165x.2014.05.017

中国临床解剖学杂志 ›› 2014, Vol. 32 ›› Issue (5): 580-584.doi: 10.13418/j.issn.1001-165x.2014.05.017

大鼠背部穿支体区间choke血管变化规律初探

胡斯旺^1,4，　庄跃宏²，　崔怀瑞^1,3，　黄美贤¹，　唐茂林³，　徐达传¹

1.南方医科大学临床解剖学研究所，广州 510515； 2. 福建医科大学解剖学教研室，福州 350108；
3. 温州医科大学解剖学教研室，温州 325035；　4. 宁波大学医学院附属医院脊柱外科, 浙江宁波 315000

收稿日期:2014-02-06 出版日期:2014-09-25 发布日期:2014-10-14
通讯作者: 徐达传，教授，博士生导师，Tel：（020）61648202，E-mail：chjcana@126.com E-mail:184037873@qq.com
作者简介:胡斯旺（1979-），男，浙江玉环人，博士，研究方向：临床解剖学
基金资助:
国家自然科学基金（81071576）；宁波市自然科学基金（2014A610278）

Study on enlargement law of choke vessels between bilateral iliolumbar perforators in rat

HU Si-wang^1,4, ZHUANG Yue-hong ², CUI Huai-rui ^1,3, HUANG Mei-xian ¹, TANG Mao-lin³, XU Da-chuan ¹

1. Institute of Clinical Anatomy, Southern Medical University, Guangzhou 510515, China; 2. Department of Anatomy, Fujian Medical University, Fuzhou 350108, China; 3. Department of Anatomy, Wenzhou Medical University, Wenzhou 325035, China; 4. Department of Spine Surgery, Affiliated Hospital of Medical College of Ningbo University, Ningbo 315000, China

Received:2014-02-06 Online:2014-09-25 Published:2014-10-14

摘要/Abstract

摘要：

目的　设计可对大鼠背部穿支体区间choke血管进行直视观察的模型，并进一步探索choke血管扩增的规律。方法　制作皮肤血管观察窗套件，选择左、右髂腰动脉穿支体区间的微血管吻合（即choke血管）作为目标观察区，并分时间点在体视显微镜下观察choke血管的扩增，测量并计算微血管在各时间点的“扩增率”，总结其扩增规律。结果　设计的皮肤观察窗套件可清楚观察到大鼠皮肤血管的扩增过程，该观察窗套件还可根据观察对象的大小调整尺寸进而观察不同动物的choke血管。通过对大鼠背部穿支体区间choke血管观察发现第1h、1d、2d、3d、4d、6d、10d、16d目标观察区choke血管的“扩增率”分别是（1.00±0.00）、（1.11±0.08）、（1.25±0.17）、（1.36±0.22）、（1.85±0.33）、（1.82±0.38）、（1.54±0.39）和（1.83±0.45）。结论　对于皮肤微血管的活体动物研究，皮窗结合体视显微镜观察是方便、有效的直视观察手段。大鼠两髂腰动脉穿支体间的choke血管在第4~6天时处于扩增高峰，逐渐减弱后在第10~16天出现二次扩增。

关键词: 皮窗, 穿支体区, choke血管, 血管造影

Abstract:

Objective　To design direct observation model of choke vessels between bilateral iliolumbar perforators in rats and explore the enlargement law of choke vessels.　Methods　skinfold chamber was designed and produced, then anastomotic vessels (known as choke vessels) were chosen as observation area between the right and left iliac lumbar perforasomes. The changes of choke vessel in the observation area were photographed at different time points by using stereomicroscope. The enlargement ratio of choke vessel was measured and calculated in each time point, with the law of enlargement drawn.　Results The enlargement course of the choke vessels between the bilateral iliolumbar perforators can be observed by the skinfold chamber, whose size can be adjusted to observe choke vessels in different animals. After observation，we found that the enlargement-ratio of choke vessels in 1h, 1d, 2d, 3d, 4d, 6d, 10d, 16d were (1.00±0.00), (1.11±0.08), (1.25±0.17), (1.36±0.22), (1.85±0.33), (1.82±0.38), (1.54±0.39) and (1.83±0.45) respectively. Conclusions　The skinfold chamber is a convenient, effective and direct way to observe cutaneous microvessels in rats alive using stereomicroscope. The choke vessels between the iliolumbar perforasomes in rat gets a highest enlargement ratio in 4 d to 6 d, then recedes gradually until 10 d to 16 d when it gets a second boost.

Key words: Skinfold chamber, Perforasomes, Choke vessel, Angiography

中图分类号:

R322
R616.2

胡斯旺, 庄跃宏, 崔怀瑞, 黄美贤, 唐茂林, 徐达传. 大鼠背部穿支体区间choke血管变化规律初探[J]. 中国临床解剖学杂志, 2014, 32(5): 580-584.

HU Shi-Wang, PENG Ti-Hong, CUI Fu-Rui, HUANG Mei-Xian, TANG Mao-Lin, XU Da-Chuan. Study on enlargement law of choke vessels between bilateral iliolumbar perforators in rat[J]. Chinese Journal of Clinical Anatomy, 2014, 32(5): 580-584.

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大鼠背部穿支体区间choke血管变化规律初探

Study on enlargement law of choke vessels between bilateral iliolumbar perforators in rat

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