人丘脑及相关重要结构的断面解剖学研究
张华, 周庭永, 钱学华, 郑登儒, 刘智华, 白桂芹, 吕发金
中国临床解剖学杂志 ›› 2012, Vol. 30 ›› Issue (4) : 393-397.
人丘脑及相关重要结构的断面解剖学研究
Morphological measurement of the thalamus and thalamus-related structures
目的 为丘脑及其相关重要结构的影像诊断提供形态学依据和相关测值。 方法 采用30例正常成人头颅标本(男17例,女13例),取平行于眦耳线平面制成片厚5 mm的连续横断面。各选取丘脑及其相关重要结构所在的3个连续断面,对其进行观测,数据经标准化处理后进行相关统计处理。 结果 丘脑面积、横径和矢径在性差和侧差方面未见显著性差异。丘脑面积与尾状核头面积、以及与尾状核头横径呈负相关(P<0.05),丘脑横径与尾状核头面积、矢径呈负相关(P<0.05);丘脑长与端脑长、丘脑宽与端脑宽分别呈正相关(P<0.05),左丘脑长与脑型呈负相关(P<0.05),左丘脑型与脑型呈正相关(P< 0.05),丘脑夹角与脑型呈正相关(P<0.05),丘脑长与右三角区至前角间距存在相关关系(P<0.05)。 结论 丘脑形态学是否存在性差与侧差需要进一步探讨,丘脑参数与其相关重要结构参数存在线性关系,相关测值变化可为丘脑形态学变化提供信息。
Objective To provide morphological basis of the thalamus and thalamus-related structures for imaging diagnosis. Methods Totally 30 adult head specimens were used to make serial transverse sections along canthomeatal 1ine (CML), with the thickness of 5 mm. The three continuous sections involving thalamus and its relative structures were observed and statistically analyzed. Results After adjusting cerebral volume, the area, sagittal and transverse diameters of bilateral thalamus had no gender difference. Negative correlation appeared among thalamus area, caudate nucleus head area, and the transverse diameter of the caudate nucleus head(P<0.05). The transverse diameter of the thalamus and the area of the caudate nucleus head, as well as the sagittal diameter of the caudate nucleus head was negatively related (P<0.05). The length and width of the thalamus and the telencephalon were positively related, respectively (P<0.05). The distance between right trigone of the lateral ventricle and anterior horns was significantly related with the length of the thalamus (P<0.05). Conclusions Anatomic parameters of the thalamus and thalamus-related structures have linear relationships. The data of thalamus-related structures can provide information for exploring the features of thalamus.
[1] Herrero MT, Barcia C, Navarro JM. Functional anatomy of thalamus and basal ganglia
[J]. Child's Nervous System, 2002, 18(8): 386-404.
[2] Houtchens MK, Benedict RHB, Killiany R, et al. Thalamic atrophy and cognition in multiple sclerosis
[J]. Neurology, 2007, 69(12): 1213-1223.
[3] Rao NP, Kalmady S, Arasappa R, et al. Clinical correlates of thalamus volume deficits in anti-psychotic-na?ve schizophrenia patients: A 3-Tesla MRI study
[J]. Indian Journal of Psychiatry, 2010, 52(3): 229-235.
[4] Jennifer LW,?William RC, Hilary CW, et al. Normalization of cerebral volumes by use of intracranial volume: implications for longitudinal quantitative MR imaging
[J]. American Journal of Neuroradiology, 2001, 22(8): 1483-1489.
[5] John A, Karl JF. Why voxel-based morphometry should be used
[J]. Neuroimage, 2001, 14(6): 1238-1243.
[6] Zangwill OL. Speech and the minor hemisphere
[J]. Acta Neutologica et Psychiatrica Belgica, 1967, 67: 1013-1020.
[7] Daniel AA, Trent N, Steven Z, et al. Right-hemisphere auditory cortex is dominant for coding syllable patterns in speech
[J]. The Journal of Neuroscience, 2008, 28(15): 3958-3965.
[8] Xie Y, Chen YA, De Bellis MD. The relationship of age, gender, and IQ with the brainstem and thalamus in healthy children and adolescents: a magnetic resonance imaging volumetric study
[J]. Journal of Child Neurology, 2011, 9: 1-7.
[9] Sullivan EV, Rosenbloom M, Serventi KL, et al. Effects of age and sex on volumes of the thalamus, pons, and cortex
[J]. Neurobiology of Aging, 2004, 25(2): 185-192.
[10]Csernansky JG, Csernansky K, Splinter NR, et al. Abnormalities of thalamic volume and shape in schizophrenia
[J]. Am J Psychiatry, 2004, 161(5): 896-902.
[11]Ahsan RL, Allom R, Gousias IS, et al. Volumes, spatial extents and a probabilistic atlas of the human basal ganglia and thalamus
[J]. Neuroimage, 2007, 38(2): 261-270.
[12]Sowell ER, Trauner DA, Gamst A, et al. Development of cortical and subcortical brain structures in childhood and adolescence: a structural MRI study
[J]. Dev Med Child Neurol, 2002, 44(1): 4-16.
[13]De Jong LW, Van der Hiele K, Veer IM, et al. Strongly reduced volumes of putamen and thalamus in Alzheimer's disease: an MRI study
[J]. Brain, 2008; 131(12):3277-85.
[14] Gaser C, Nenadic I, Buchsbaum BR, et al. Ventricular enlargement in schizophrenia related to volume reduction of the thalamus, striatum, and superior temporal cortex
[J]. Am J Psychiatry 2004, 161(1): 154-156.
[15] 陈晓光,林志国,王晓峰,等. 帕金森病手术相关靶点MRI定位研究
[J]. Chinese Journal of Neurosurgery, 2004, 20(4): 283-287.
[16] Schaltenbrand G, Wahren W. Guide to the atlas for stereotaxy of the human brain. In: atlas for stereotaxy of the human brain
[M]. Georg Thieme Publisher: Stuttgart, 1977: 1-7.
[17] 姚家庆,戴恒茹. 大脑半球、第三脑室与丘脑之间规律性的探索
[J].解剖学杂志, 1987, 10(4): 295-297.
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