MRI三维重建及旋转分割法对膝关节骨性关节炎患者半月板形态、位置变化的临床对比研究

doi:10.13418/j.issn.1001-165x.2015.04.008

中国临床解剖学杂志 ›› 2015, Vol. 33 ›› Issue (4): 408-413.doi: 10.13418/j.issn.1001-165x.2015.04.008

MRI三维重建及旋转分割法对膝关节骨性关节炎患者半月板形态、位置变化的临床对比研究

孔令伟¹，　崔志新²，　王瑜²，　赵景新²，　纪海茹¹，　孔祥玉¹，　金宇²

1.承德医学院，河北承德 067000；　2.承德医学院附属医院, 河北承德 067000

收稿日期:2014-05-18 出版日期:2015-07-25 发布日期:2015-08-14
通讯作者: 金宇，主任医师，研究生导师，E-mail：358620793@qq.com
作者简介:孔令伟（1988-），男，满族，河北承德人，在读硕士，Tel：13832428328，E-mail： 358620793@qq.com
基金资助:
河北省卫生厅2012年度医学科学研究重点课题计划项目（20120165）

Clinical comparative study on morphology and positional changes of meniscus in patients with knee osteoarthritis-By Magnetic resonance imaging 3D reconstruction and rotation segmedtation methods

KONG Ling-wei¹, CUI Zhi-xin², WANG Yu², ZHAO Jing-xin², JI Hai-ru¹, KONG Xing-yu¹, JIN Yu²

1.Chengde Medical Colloge, Chengde 067000, China; 2.The Affiliated Hospital of Cheng de Medical College, Chengde 067000, China

Received:2014-05-18 Online:2015-07-25 Published:2015-08-14

摘要/Abstract

摘要：

目的　利用MRI三维重建及旋转分割方法对膝骨性关节炎患者及正常人半月板的形态及位置进行定量测量并对比分析，探讨膝骨性关节炎患者半月板的形态、位置变化及其临床意义。方法　选取2013年1月-2014年2月在我院诊治的膝骨性关节炎II、III级患者20例（共20膝）作为关节炎组，另选择年龄、性别、体重指数相匹配的正常人10例（共10膝）作为正常组。所有研究对象先行MRI 3D薄层扫描，后行三维重建及旋转分割，在分割后的图像上对半月板进行定量测量，以半月板整体宽度、半月板覆盖胫骨平台宽度和半月板厚度作为量化指标进行两组间对比研究。结果　内侧半月板整体宽度在所有方向上两组间差异无统计学意义；覆盖胫骨平台宽度从60°~120°位关节炎组明显变小，两组间差异具有统计学意义；厚度在60°~130°位关节炎组明显变厚，两组间差异具有统计学意义。外侧半月板整体宽度及覆盖胫骨平台宽度在10°~50°及140°~170°位关节炎组显著变宽，两组间差异具有统计学意义；厚度在120°~170°位关节炎组明显变厚，两组间差异有统计学意义。结论　本研究为临床上半月板的MRI检查提供了一个新的方法和思路；通过测量发现膝骨性关节炎患者半月板的形状、位置与正常人相比发生了明显的变化，且这种变化同膝关节骨性关节炎具有一定相关性。

关键词: 半月板, 定量测量, 磁共振成像, 旋转分割, 骨性关节炎

Abstract:

Objective　Using the magnetic resonance imaging 3D reconstruction and rotation segmentation methods to measure the meniscuses of patients with knee osteoarthritis and normal adults, and the morphological and positional changes of the meniscus on patients with osteoarthritis and its clinical significance were explored.　Methods　20 cases of patients with knee osteoarthritis (II, III grade) involving 20 knee joints were selected from our hospital as osteoarthritis group between January 2013 to February 2014. The other,10 cases of normal people, involving 10 knee joints were chosen as a normal group. The age, sex, body mass index were matched between the two groups. Firstly, all subjects were scanned using thin slices of MRI, and the images obtained were then transferred for the post-processing workstation of Siemens for three-dimensional reconstruction and segmentation of the images using the method of range radials. Lastly, the meniscus was measured in the images we segmented. The entire width of meniscus, the width covering the tibia platform of the meniscus and the thickness of the meniscus were measured for quantitative indicators to study.　Results　No significant differences was found between the two groups in the entire width of medial meniscus in all directions, whereas, the width covering the tibia platform of the meniscus from 60° to 120° was smaller in OA than in non-OA knees (P＜0.05) and the thickness of the medial meniscus from 60 °to 130 ° was thicker in OA than in non-OA knees (P＜0.05). There were significant differences in measurement of the lateral meniscus between the two groups. The entire width and the width covering the tibia platform of lateral meniscus from 10° to 50° and 10° to 50° were greater in OA than in non-OA knees (P＜0.05) and the thickness of the lateral meniscus from 120° to 170° were thicker in OA than in non-OA knees (P＜0.05). Conclusions　The study provides a new check method and train of thought for display and diagnosis of the meniscus with MRI. It is found that the morphology and positions of the meniscus in patients with osteoarthritis have changed and this changes are associated with knee osteoarthritis.

Key words: Meniscus, Quantitative measurement, Magnetic resonance imaging, Radial ranges, Osteoarthritis

孔令伟,崔志新,王瑜,赵景新,纪海茹,孔祥玉,金宇. MRI三维重建及旋转分割法对膝关节骨性关节炎患者半月板形态、位置变化的临床对比研究[J]. 中国临床解剖学杂志, 2015, 33(4): 408-413.

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MRI三维重建及旋转分割法对膝关节骨性关节炎患者半月板形态、位置变化的临床对比研究

Clinical comparative study on morphology and positional changes of meniscus in patients with knee osteoarthritis-By Magnetic resonance imaging 3D reconstruction and rotation segmedtation methods

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