关键词:  , 富血小板血浆, 　股骨头坏死, 　高位头颈开窗, 　植骨

Abstract:

Objective　To investigate the potency of the platelet-rich plasma（PRP）combined with the bone grafting through a femoral neck window at high location for the treatment of the osteonecrosis of the femoral head.　Methods　From July 2015 to July 2017, 18 cases（27 hips）of osteonecrosis of the femoral head were treated with platelet-rich plasma combined with core decompression and ilium support（PRP group）and 16 cases（24 hips）with core decompression and ilium support only（control group）. At 1, 3，and 6 months after operation, patients were followed up for Harris hip score，VAS score and radiographic measures.　Results　All the patients were followed up thoroughly and the follow-up periods were 6 months. At 6 months after operation, the shape of the femoral heads in the PRP groups was good, showing no deformation and collapse. The ilium made integration with the surrounding bone without infection. Harris score of PRP group before and after treatment increased from（67.85±9.72）points to（88.51±6.13）points. Harris score of control group before and after treatment increased from（69.85±8.15）points to（78.42±6.28）points. VAS score of PRP group before and after treatment increased from（4.5±1.3）points to（1.6±1.1）points. VAS score of control group before and after treatment increased from（4.2±0.8）points to（2.4±0.9） points. There were statistically significant differences between two groups. There were statistically significant differences in the pre-therapy and post-treatment (P<0.05). There were statistically significant differences in the post-operation between two groups (P<0.05).　Conclusions　Use the platelet-rich plasma（PRP）in clinical can relieve hip pain and improve joint function, and is thus highly valuable in clinical use．

Key words: Platelet-rich plasma;　Osteonecrosis of the femoral head;　Femoral neck window at high location;   , Bone grafting