中国临床解剖学杂志 ›› 2019, Vol. 37 ›› Issue (6): 680-685.doi: 10.13418/j.issn.1001-165x.2019.06.014

• 临床生物力学 • 上一篇    下一篇

鼓膜-听骨链精细三维重建及谐响应有限元分析

胡力达1, 田广永1, 徐飘2, 林琼萍2   

  1. 1.南方医科大学第三附属医院耳鼻咽喉头颈外科,  广州   510630;   2.南方医科大学第三临床医学院,  广州   510630
  • 收稿日期:2019-01-20 出版日期:2019-11-25 发布日期:2019-12-03
  • 通讯作者: 田广永,教授,主任医师,E-mail:782683004@qq.com
  • 作者简介:胡力达(1990-),男,硕士研究生,住院医师,主要研究方向:听力系统数字化三维重建及生物力学分析,E-mail:248051069@qq.com

3D reconstruction of sophisticated eardrum-ossicular chain model and the harmonic response analysis calculated by finite element method

HU Li-da1, TIAN Guang-yong1, XU Piao2, LIN Qiong-ping2   

  1. 1. Department of ENT & HN Surgery, the 3rd Affiliated Hospital of Southern Medical University, Guangzhou 510630; 2. The 3rd Clinical Medical School of Southern Medical University, Guangzhou 510630
  • Received:2019-01-20 Online:2019-11-25 Published:2019-12-03

摘要: 目的 建立精细化的鼓膜-听骨链三维模型,并通过有限元方法进行生物力学分析,验证模型的合理性,为后续实验提供理论基础及依据。  方法 通过Micro-CT获取精细断层数据(螺距0.24 mm,断层图像共464张),利用多软件综合处理,数字化重建鼓膜-听骨链,使用有限元进行谐响应振动力学分析,与激光多普勒在颞骨标本上获取的相应数据进行对比分析。  结果 数字化重建的鼓膜-听骨链模型,于100Hz、800Hz、8000Hz处,鼓膜数据采集点振幅分别为0.022μm、0.031μm、0.0041μm,镫骨足板数据采集点振幅分别为0.011μm、0.015μm、0.000069μm,各频率对应振幅与激光多普勒所得结果区间相符,趋势一致。  结论 利用该方法建立的模型,可以有效的数字化还原鼓膜-听骨链,后续可通过该模型,进一步实验分析听骨链生理及病理模型。

关键词: 鼓膜-听骨链,  有限元,  生物力学,  谐响应分析,  数字化重建

Abstract: Objective To verify the reliability of the sophisticated eardrum-ossicular chain model and provide theoretical basis and reference for the follow-up experiments by using finite element method to analyze the harmonic response. Methods A sophisticated eardrum-ossicular chain model by multi-software synthesized was established, by using Micro-CT and finite element method to obtain the fault data (screw pitch:0.24mm, total cross sectional image: 464 slices). The fault data were compared with the data which obtained from the temporal bone specimen scanned by laser doppler. Results The amplitudes of the tympanic membrane data collection points were 0.022, 0.031 and 0.0041 microns at frequency of 100Hz, 800Hz, 8000Hz respectively, and the amplitudes of the stapes plate data collection points were 0.011, 0.015 and 0.000069 microns respectively. The result of the models’ harmonic response was consistent with the result of laser doppler. Conclusions We can rebuild effectively a sophisticated eardrum-ossicular chain by establishing the model, we can use this model to analyze physiological function and pathologic change of the ossicular chain.

Key words: Eardrum-ossicular chain model,  FEM,  Biomechanics,  Harmonic response analysis, Digital reconstruction

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