中国临床解剖学杂志 ›› 2018, Vol. 36 ›› Issue (2): 147-152.doi: 10.13418/j.issn.1001-165x.2018.02.006

• 断层影像解剖 • 上一篇    下一篇

头部CT三维重建在鼻窦内翻性乳头状瘤术前规划的应用

蔡丽1, 马建刚1, 于磊1, 毛昳楠1, 周鲲鹏2, 杨彦忠1, 任国山3   

  1. 1. 河北医科大学第二医院耳鼻咽喉科,  石家庄   050000; 2. 河北省石家庄市第一医院耳鼻咽喉科,  石家庄   050000
    3. 河北医科大学,  石家庄   050000
  • 收稿日期:2017-06-25 出版日期:2018-03-25 发布日期:2018-05-04
  • 通讯作者: 任国山,教授,硕士生导师,E-mail: rengsh2004@126.com
  • 作者简介:蔡丽(1971-),硕士,主任医师,主要从事耳鼻咽喉头颈外科,尤其是鼻科及侧颅底的相关临床和基础研究,Tel:(0311)66003788,E-mail:ent-cl@163.com

Application of head CT 3D-reconstruction for operation planning of nasal inverted papilloma

CAI Li1,MA Jian-gang1,YU Lei1, MAO Yi-nan1,ZHOU Kun-peng2,YANG Yan-zhong1, REN Guo-shan3   

  1. 1. Department of Otolaryngology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China; 2. Department of Otolaryngology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, China; 3. Hebei Medical University, Shijiazhuang 050000, China
  • Received:2017-06-25 Online:2018-03-25 Published:2018-05-04

摘要:

目的 通过基于头部CT的三维重建技术,对复杂的内翻性乳头状瘤进行手术规划,为临床推广应用提供参考。 方法 本实验选取一名男性患者,65岁,体重70 kg,身高170 cm,无头部外伤史、手术史、颅脑疾病家族史。行头部CT平扫,排除脑组织器质性疾病。已和患者签署知情同意书。将头部CT图像通过逆向工程软件Mimics 15.0建立三维立体模型,将手术仿真成功的三维模型组件在3-Matic 7.0进行测量,对鼻窦内翻性乳头状瘤患者进行手术规划设计及术后随访观察。 结果 建立了与CT图像测量结果一致的颅骨、鼻窦及肿瘤的三维立体模型;建立了与手术入路一致的仿真鼻部通道的三维模型;确定了复杂鼻部肿瘤的手术方案及预后评估。术中切除肿瘤组织测量结果为X轴最大值为64.78 mm,Y轴71.21 mm,Z轴86.46 mm,总体积为58.88 ml,其形态、大小与术前三维重建测量分析结果基本一致。 结论 根据三维立体模型分析得出的数据设计手术方案,有助于顺利完成手术,对个体化鼻窦肿瘤手术设计具有重要的临床指导意义。

关键词: 内翻性乳头状瘤,  鼻窦,  手术规划,  逆向工程,  三维重建

Abstract:

Objective To use the technology of three-dimensional (3D)reconstruction based on head CT for  preoperation  planning and postoperative  assessment in the nasal inverted papilloma surgery, and to provide reference value for clinical application. Method This study selected a male patient, who was 65 years old with a weight of 70 kg and height of 170 cm, and had  no head trauma history, surgery history and family history of brain disease. Head CT scans were performed to exclude organic brain diseases. Informed consent has been signed with the patient. The reverse engineering software Mimics 15.0 was used to create a 3D-reconstruction model, the model components were measured by 3-matic 7.0, and the preoperative planning and follow-up observation for the nasal inverted papilloma operation were designed. Result The 3D-models of head skull and sinus were established in accordance with the CT image measurement results;  a 3D model of simulated nasal passages and tumors that consistent with the surgical approach was established; the surgical design of complicated nasal tumor and assessment after eradication were further completed. Postoperative tumor measurements showed a maximum diameter of 64.78 mm on the X-axis, 71.21 mm on the Y-axis, 86.46 mm on the Z-axis, and a total volume of 58.88 ml. This was in accord with the preoperative measurement results in shape and size. According to the analysis, the size of the tumor tissue resected during the operation was basically the same as the size of the preoperative 3D-model reconstructed tumor, indicating that the tumor tissue was completely resected by the operation. Conclusion Through the data analyzed by the 3D model,  we can design pre-operation  planning and complete the operation successfully. It is of great significance to guide the clinical design of individualized surgical approach for sinus tumors.

Key words: Nasal inverted papilloma,  Accessory nasal sinuses,  Operation planning,  Reverse engineering,  3D reconstruction