关键词: 蛛网膜颗粒, 　核磁共振成像, 　年龄, 　脑脊液

Abstract: Objective　To study the relationship between the arachnoid granulation (AG) in dural sinus and age.    Methods    The clinical and imaging data of 360 patients with intracranial no abnormalities were collected according to the age. The distribution of AG in venous sinus and the shape, size, number and the changes of morphology in the same patients of AG in each age group were observed.    Results    MR examination showed that the most common site of AG was transverse sinus, followed by superior sagittal sinus, straight sinus, torcular, cavernous sinus. With the increasing of age in the juveniles patients group, the AG diameter became larger, the quantity and the number of lobulated of AG gradually increased. With the increasing of age in the middle-aged patients group, the diameter and number fluctuations in the fixed range, the shape remained basically unchanged. There were statistical difference in the number and diameter of patients who could detect AG between the juveniles group and the middle-aged group. With the increasing of age in the old-aged patients group, the AG diameter became small, number and the number of lobulated also reduced. There were statistical difference in the number and diameter of patients who could detect AG between the middle-aged group and the old-aged group.    Conclusions    The number, size and shape of the arachnoid granulation are variable in different age groups, and these changes may be closely related to growth and development, aging and regulation of cerebrospinal fluid reabsorption. 

Key words: Arachnoid granulation, 　Magnetic resonance imaging, 　Age, 　Cerebrospinal fluid ,