应用GQI技术对小脑髓质的初步研究

doi:10.13418/j.issn.1001-165x.2014.01.009

中国临床解剖学杂志 ›› 2014, Vol. 32 ›› Issue (1): 36-40.doi: 10.13418/j.issn.1001-165x.2014.01.009

应用GQI技术对小脑髓质的初步研究

陈一勇¹，　尹维刚¹，　林荣¹，　王守道¹，　汪海清¹，　李林²

1.宁波大学医学院，浙江宁波 315211；　2.南京医科大学解剖教研室，南京 210029

收稿日期:2013-09-10 出版日期:2014-01-25 发布日期:2014-02-11
通讯作者: 李林，博士，讲师， E-mal: lilin5917@gmail.com E-mail:chenyiyong@nbu.edu.cn
作者简介:陈一勇（1974-）男，山西汾阳人，博士，主要从事神经影像解剖学方面的研究，Tel: 13989368195

The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging

CHEN Yi-yong¹， YIN Wei-gang¹， LIN Rong¹， WANG Shou-dou¹， WANG Hai-qing¹， LI Lin²

1. Medical School of Ningbo University，Ningbo 315211，Zhejiang Province, China; 2. Department of Anatomy, Nanjing Medical University, Nanjing 210029, China

Received:2013-09-10 Online:2014-01-25 Published:2014-02-11

摘要/Abstract

摘要：

目的　应用基于GQI的弥散成像方法，对小脑的纤维束进行重建和显示，为小脑疾病的影像诊断进行解剖学和技术上的探索。方法　首先把10例脑连接组项目的磁共振弥散数据导入DSI-studio软件，然后依次用该软件中的GQI（Generalized Q-sampling imaging）成像技术和流线算法（streamline algorithm）对与小脑有关的纤维束进行重建和显示。结果　（1）在DSI-studio软件的二维和三维界面中显示了小脑三对脚的位置和交叉情况；（2）显示了小脑3对脚与脊髓、延髓、脑桥、中脑、端脑等的连接情况及其主要纤维成分。结论　应用GQI技术可以对小脑白质进行重建和显示，为小脑疾病的影像学诊断提供技术和结构学上的帮助。

关键词: GQI, 脑连接组项目, DSI-studio软件, 小脑髓质

Abstract:

Objective　To show the fibers that connected the cerebellum with brainstem, diencephalon and spinal cord using GQI.　Methods　We acquired high-resolution structural and diffusion MRI of 10 subjects from HCP. The tractography based on a GQI and streamline algorithm of the DSI-studio software was performed to reconstruct and show the fibers that linked the cerebellum with other parts of the CNS(Central Nervous System).　Results　(1) 2-dimensional and 3-dimensional positions and intersections of the superior (SCP), and middle (MCP) and inferior (ICP) cerebellar peduncles were showed using the DSI-studio software. (2) the main ingredients of the three peduncles of cerebellum which connected to the spinal cord, medulla oblongata, pons, midbrain, diencephalon were 3-dimensionally demonstrated.　Conclusions　The cerebellum medulla can reconstructed and displayed using GQI, providing a diagnostic tool for characterizing anatomical disruptions that occur in cerebellar diseases and for monitoring response to therapeutic interventions.

Key words: Generalized Q-sampling Imaging(GQI), Human Connectome Project(HCP), DSI-studio software, Medulla of cerebellum

中图分类号:

R323

陈一勇, 尹维刚, 林荣, 王守道, 汪海清, 李林. 应用GQI技术对小脑髓质的初步研究[J]. 中国临床解剖学杂志, 2014, 32(1): 36-40.

CHEN Yi-Yong, YIN Wei-Gang, LIN Rong, WANG Shou-Dao, HONG Hai-Qing, LI Lin. The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging[J]. Chinese Journal of Clinical Anatomy, 2014, 32(1): 36-40.

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应用GQI技术对小脑髓质的初步研究

The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging

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