基于人脑纹状体与海马结构的断层影像学研究

doi:10.13418/j.issn.1001-165x.2015.04.005

中国临床解剖学杂志 ›› 2015, Vol. 33 ›› Issue (4): 393-398.doi: 10.13418/j.issn.1001-165x.2015.04.005

基于人脑纹状体与海马结构的断层影像学研究

白桂芹¹，　刘尚清¹，　张华¹，　邓世山¹，　谢兴国¹ ，　蔡昌平¹，　黄小华²，　张小明²

1.川北医学院解剖学教研室，四川南充 637007； 2.川北医学院附属医院放射科，四川南充 637007

收稿日期:2014-10-19 出版日期:2015-07-25 发布日期:2015-08-14
通讯作者: 刘尚清，博士，教授，E-mail：sandrich@qq.com
作者简介:白桂芹（1982-）女，山东济宁人，硕士，主要从事临床应用解剖与断层影像解剖学研究，Tel：18281731246，E-mail：491602723@qq.com
基金资助:
川北医学院科研发展计划项目(CBY-13-A-QN27)

Tomographic imaging study of human brain corpus striatum and hippocampus structure

BAI Gui-qin¹，LIU Shang-qing¹，ZHANG Hua¹，DENG Shi-shan¹， XIE Xing-guo¹，CAI Chang-ping¹， HUANG Xiao-hua²，ZHANG Xiao-ming²

1. Department of Anatomy，North Sichuan Medical University，Nanchong, Sichuan 637007; 2. Department of Radiology, the Affiliated Hospital, North Sichuan Medical University，Sichuan 637007, China

Received:2014-10-19 Online:2015-07-25 Published:2015-08-14

摘要/Abstract

摘要：

目的　探讨纹状体与海马结构的相关性，为临床影像诊断提供形态学依据和相关测值。方法　采集100例经诊断无病变的成人头部磁共振图像，按照年龄16～25、26～35、36～45、46～55、 56～65岁进行分组，每组男、女各10例。观测纹状体与海马结构的面积、横径、矢径等线性指标，标准化前、后数据均进行相应统计学处理。结果　数据经标准化处理后，运用单因素方差分析显示：纹状体面积无性差，尾状核头矢径、海马面积、海马横径、矢径存在性差(女性>男性)，颞角宽度存在性差(女性<男性)；尾状核头横径存在侧差（左>右），壳面积、壳矢径存在侧差（左<右）。利用Pearson相关分析显示：纹状体面积与年龄、颞叶钩回间距呈负相关，与颞角宽度呈正相关；海马面积与尾状核头面积、颞角宽度呈正相关。结论　成年人纹状体面积随着年龄增长而缩小；海马结构与纹状体在形态结构上具有相关性；壳面积右侧大于左侧；女性海马面积大于男性；颞角宽度可以作为研究纹状体与海马结构形态变化的共同参考指标。

关键词: 纹状体, 海马结构, 断层影像解剖, MRI

Abstract:

Objective　To investigate the correlation between corpus striatum and hippocampus structure, and provide the morphological evidence and related measurement value for clinical imaging diagnosis.　Methods　Magnetic resonance images of 100 cases of adult heads without pathological changes were collected and divided into five groups falling into five age ranges : 16 ~ 25, 26 ~ 35, 36 ~ 45, 46 ~ 55, 56 ~ 65 years old, with 10 males and 10 females in each age range. Parameters such as the area, the transverse and vertical diameter of the corpus striatum and hippocampus were obtained and underwent statistical analyses.　Results　After standardization of data, the outcome of the single factor analysis of variance showed: There was no gender difference in striatum area; The sagittal diameter of caudate head, the hippocampus area, and the transverse and sagittal diameter of the hippocampal structure exhibited gender difference ( female>male ); The width of the temporal horn of the male was larger than the female；The transverse diameter of the caudate nucleus head exhibited side difference (left>right)，while the right putamen area and the sagittal diameter was greater than on the left. Pearson correlation analysis showed: The head of caudate nucleus area was negatively related with age and the distance between the temporal lobe hooks, but was positively related with the width of the temporal horn. The hippocampal area was positively related with the head of caudate nucleus area and the width of the temporal horn.　Conclusion　The adult corpus striatum shrank with the increase of age; There was correlation between the hippocampus structure and corpus striatum on the morphology. The right putamen area was greater than the left. The female hippocampus area was greater than the male. The width of the temporal horn can be used as common references indicators in morphological research of the striatum and hippocampus.

Key words: Corpus striatum, Hippocampus structure, Sectional and imaging anatomy, MRI

白桂芹,刘尚清,张华,邓世山,谢兴国,蔡昌平,黄小华,张小明 . 基于人脑纹状体与海马结构的断层影像学研究[J]. 中国临床解剖学杂志, 2015, 33(4): 393-398.

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基于人脑纹状体与海马结构的断层影像学研究

Tomographic imaging study of human brain corpus striatum and hippocampus structure

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