关键词: 自体颗粒骨打压植骨, 　自体骨cage植骨, 　椎体间融合术

Abstract:

Objective　To retrospectively study the clinical effect of two improved autologous bone lumber interbody fusion methods (autogenous bone interbody fusion cage(ABIF) and autogenous morselized bone graft impaction(AMBI)) compared with the PEEK cage fusion.　Methods　The clinical data of 110 cases of patients who took the lumber fusion surgery from 2010 to 2016 were collected. All the cases were divided into three groups by the fusion method: AMBI:36 cases, ABIF:35 cases, PEEK:39 cases. The VAS score, ODI score at the time point of pre-operation, 6 months post-operation and 12 months post-operation were evaluated, the loss of intervertebral space height on X-ray and the relative fusion rate on CT scanning at the time point of 24 h post-operation, 6 months post-operation and 12 months post-operation was evaluated. The general information of three groups had no statistical significance, indicating good comparability of the three groups.　Result　All three groups had no serious complications. The loss of intervertebral space height 6m and 12 m post-operation of each group: AMBI:(6.1±2.5、6.5±3.8)%, ABIF:(5.6±2.9、5.8±3.7)%；PEEK:(5.4±3.3、5.9±4.1)%,the relative fusion rate 6 months and 12 months post-operation of each group: AMBI:(27.5±10.5、26.5±9.1)%, ABIF:(31.2±8.7、28.1±8.7)%, PEEK:(28.4±7.1、29.3±8.2)%。Statistical results showed VAS score, ODI score, loss of intervertebral space height and the relative fusion rate 6m and 12m post-operation of each group have no statistical significance (P＞0.05).    Conclusion　All three groups have the same clinical effect and fusion rate, the result indicate a good promise of clinical application of AMBI and ABIF.

Key words: Autogenous bone interbody fusion;　Autogenous morselized bone graft impaction, Interbody fusion