应用GQI技术对小脑髓质的初步研究

doi:10.13418/j.issn.1001-165x.2014.01.009

Chinese Journal of Clinical Anatomy ›› 2014, Vol. 32 ›› Issue (1): 36-40.doi: 10.13418/j.issn.1001-165x.2014.01.009

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The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging

CHEN Yi-yong¹， YIN Wei-gang¹， LIN Rong¹， WANG Shou-dou¹， WANG Hai-qing¹， LI Lin²

1. Medical School of Ningbo University，Ningbo 315211，Zhejiang Province, China; 2. Department of Anatomy, Nanjing Medical University, Nanjing 210029, China

Received:2013-09-10 Online:2014-01-25 Published:2014-02-11

Abstract

Abstract:

Objective　To show the fibers that connected the cerebellum with brainstem, diencephalon and spinal cord using GQI.　Methods　We acquired high-resolution structural and diffusion MRI of 10 subjects from HCP. The tractography based on a GQI and streamline algorithm of the DSI-studio software was performed to reconstruct and show the fibers that linked the cerebellum with other parts of the CNS(Central Nervous System).　Results　(1) 2-dimensional and 3-dimensional positions and intersections of the superior (SCP), and middle (MCP) and inferior (ICP) cerebellar peduncles were showed using the DSI-studio software. (2) the main ingredients of the three peduncles of cerebellum which connected to the spinal cord, medulla oblongata, pons, midbrain, diencephalon were 3-dimensionally demonstrated.　Conclusions　The cerebellum medulla can reconstructed and displayed using GQI, providing a diagnostic tool for characterizing anatomical disruptions that occur in cerebellar diseases and for monitoring response to therapeutic interventions.

Key words: Generalized Q-sampling Imaging(GQI), Human Connectome Project(HCP), DSI-studio software, Medulla of cerebellum

CLC Number:

R323

CHEN Yi-Yong, YIN Wei-Gang, LIN Rong, WANG Shou-Dao, HONG Hai-Qing, LI Lin. The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging[J]. Chinese Journal of Clinical Anatomy, 2014, 32(1): 36-40.

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The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging

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