[1] Jalowiecki P, Rudner R, Gonciarz M, et al. Sole use of dexmedetomidine has limited utility for conscious sedation during outpatient colonoscopy
[J].Anesthesiology, 2005,103(2):269-273.

[2] Chiu KM,Lin TY,Lu CW,et al.Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by a2 adrenoceptor agonist dexmedetomidine
[J] .Eur J Pharmacol,2011,670(1):137-147.

[3] Dahmani S, Rouelle D, Gressens P ,et al. Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions
[J].Anesthesiology,2005, l03(5):969-977

[4] Xia Z, Dickens M, Raingeaud J, et al. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
[J]. Science, 1995, 270 (240):1326-1331.

[5] DPvies SP, Reddy H, Caivano M, et al. Specificity and mechanism of action of some commonly used protein kinase inhibitors
[J]. Biochem J, 2000, 351(1):95-105.

[6] Torocsik B, Szeberenyi J. Anisomycin uses multiple mechanisms to stimulate mitogen-activated protein kinases and gene expression and to inhibit neuronal differentiation in PC12 phaeochro- mocytoma cells
[J]. Eur J Neurosci,2000，12 (2):527-532.

[7] 莫利求,兰爱平,林琳,等.右美托咪定对抗化学性低氧引起的PCl2细胞损伤
[J].中国药理学通报,20ll，27(9):l288-l292.