激光多普勒对大鼠背部3种皮瓣模型的血流动力学特点研究

doi:10.13418/j.issn.1001-165x.2016.01.003

Abstract

Abstract:

Objective　To study hemodynamic characteristics of three different patterns of flaps on the dorsum of rats. Methods　30 Sprague Dawley rat were equally divided into three groups: the perforator group, the perforator-based fasicocutaneous flap group and the random flap group. Laser Doppler flowmeter was adopted for measurement of blood perfusion on zoneⅠ、Ⅱand Ⅲ of the flaps on the three groups at the multiple time points. 7 d after surgery, photographs were taken for the flaps and the fasciocutaneous vascular network between the iliolumbar perforator and the sacrococcygeal perforator. Comparison of necrotic rates among the three groups, and comparison of perfusion values of zoneⅠ、Ⅱand Ⅲ on the perforator flap and the perforator-based fasciocutaneous flap immediately and 1d after surgery were carried out.　Results　The necrotic rates of the perforator flap, the perforator-based fasciocutaneous flap and the random flap was 0.087±0.07, 0.071±0.05 and 0.267±0.11, respectively. Immediately after surgery, the perfusion value of zoneⅠandⅡin the perforator flap group was larger than that in the perforator-based fasciocutaneous flap group with statistical significance. Perfusion value of the three zones in the random flap group was lower than their counterparts of the perforator flap group and the perforator-based fasciocutaneous flap. 7 d after surgery, the vascular network between the iliolumbar perforator and the sacrococcygeal perforator underwent tremendous enlargement in diameter.　Conclusion　There is no significant difference on the survival capacity between the perforator flap and the perforator-based fasciocutaneous flap. The survival of the random flap depends on the dilation of the vascular network between the pedicle and the nearest potential perforator.

Key words: Perforator, Fasciocutaneous, Random flap, Laser doppler flowmeter, Hemodynamics

References

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Study of hemodynamics on three different patterns of flaps on dorsum of rats

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