[1] LaFoya B, Munroe JA, Mia MM, et al. Notch: A multi-functional integrating system of microenvironmental signals[J]. Dev Biol, 2016, 418(2): 227-241.
[2]  雷蕾, 孙宁, 杜巧荣, 等. Notch信号通路在神经精神领域的研究进展[J].中华临床医师杂志(电子版), 2015, 9(5): 838-842.
[3] Kovall RA, Gebelein B, Sprinzak D, et al. The canonical Nnotch signaling pathway: structural and biochemical insights into shape, sugar, and force[J]. Dev Cell, 2017, 41(3): 228-241.
[4] Arumugam TV, Cheng YL, Choi Y, et al. Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke[J]. Mol Pharmacol, 2011, 80(1): 23-31.
[5]  Geng X, Sun T, Li JH, et al. Electroacupuncture in the repair of spinal cord injury: inhibiting the Notch signaling pathway and promoting neural stem cell proliferation[J]. Neural Regen Res, 2015, 10(3): 394-403.
[6]  Ables JL, Breunig JJ, Eisch AJ, et al. Not(ch) just development: Notch signalling in the adult brain[J]. Nat Rev Neurosci, 2011, 12(5): 269-83.
[7]  Bacigaluppi M, Russo GL, Peruzzotti-Jametti L, et al. Neural stem cell transplantation induces stroke recovery by upregulating glutamate transporter GLT-1 in astrocytes[J]. J Neurosci, 2016, 36(41): 10529-10544.
[8]  Courchesne E, Mouton PR, Calhoun ME, et al. Neuron number and size in prefrontal cortex of children with autism[J]. JAMA, 2011, 306(18): 2001-2010.
[9] Wegiel J, Kuchna I, Nowicki K, et al. The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes[J]. Acta Neuropathol, 2010, 119(6): 755-770.
[10]Stoner R, Chow ML, Boyle MP, et al. Patches of disorganization in the neocortex of children with autism[J]. N Engl J Med, 2014, 370(13): 1209-1219.
[11]Hamdan FF, Daoud H, Rochefort D, et al. De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment[J]. Am J Hum Genet, 2010, 87(5): 671-678.
[12]Braccioli L, Vervoort SJ, Adolfs Y, et al. FOXP1 promotes embryonic neural stem cell differentiation by repressing Jagged1 expression[J]. Stem Cell Reports, 2017, 9(5): 1530-1545.
[13]Phillips M, Pozzo-Miller L. Dendritic spine dysgenesis in autism related disorders[J]. Neurosci Lett, 2015, 601: 30-40.
[14]Hutsler JJ, Zhang H. Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders[J]. Brain Res, 2010, 1309: 83-94.
[15]Borghese L, Dolezalova D, Opitz T, et al. Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo[J]. Stem Cells, 2010, 28(5): 955-964.
[16]陈亦岚. Notch信号通路与孤独症大鼠神经系统发育初步研究[D]. 贵州医科大学,2016.
[17]陈亦岚, 文敏, 周波, 等. 孤独症大鼠前额叶皮质中Notch相关蛋白的表达[J]. 中国儿童保健杂志, 2016, 24(03): 260-263.
[18]Ghahramani Seno MM, Hu P, Gwadry FG, et al. Gene and miRNA expression profiles in autism spectrum disorders[J]. Brain Res, 2011, 1380: 85-97.
[19]Bailey AR, Hou H, Song M, et al. GFAP expression and social deficits in transgenic mice overexpressing human sAPPα[J]. Glia, 2013, 61(9): 1556-1569.
[20]Lebkuechner I, Wilhelmsson U, Möllerström E, et al. Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency[J]. J Neurochem, 2015, 135(2): 234-248.
[21]Tuand K, Stijnen P, Volders K, et al. Nuclear localization of the autism candidate gene neurobeachin and functional interaction with the NOTCH1 intracellular domain indicate a role in regulating transcription[J]. PLoS One, 2016, 11(3): e0151954.
[22]Griswold AJ, Ma D, Cukier HN, et al. Evaluation of copy number variations reveals novel candidate genes in autism spectrum disorder-associated pathways[J]. Hum Mol Genet, 2012, 21(15): 3513-3523.
[23]延正红, 罗海英, 徐文静, 等. NOTCH4基因位点多态性与儿童孤独症的关系[J]. 中国妇幼保健, 2010, 25(11): 1581-1582.
[24]Roos J, Grösch S, Werz O, et al. Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells[J]? Pharmacol Ther, 2016, 157: 43-64.
[25]Kay SK, Harrington HA, Shepherd S, et al. The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt[J]. PLoS Comput Biol, 2017, 13(2): e1005400.
[26]Espinosa L, Inglés-Esteve J, Aguilera C, et al. Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways[J]. J Biol Chem, 2003, 278(34): 32227-32235.
[27]Caliceti C, Nigro P, Rizzo P, et al. ROS, Notch, and Wnt signaling pathways: crosstalk between three major regulators of cardiovascular biology[J]. Biomed Res Int, 2014, 2014: 318714.
[28]Rodilla V, Villanueva A, Obrador-Hevia A, et al. Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer[J]. Proc Natl Acad Sci U S A, 2009, 106(15): 6315-6320.
[29]Ungerbäck J, Elander N, Grünberg J, et al. The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells[J]. PLoS One, 2011, 6(3): e17957.
[30]Aval SF, Lotfi H, Sheervalilou R, et al. Tuning of major signaling networks (TGF-β, Wnt, Notch and Hedgehog) by miRNAs in human stem cells commitment to different lineages: Possible clinical application[J]. Biomed Pharmacother, 2017, 91: 849-860.
[31]Zhang Y, Yuan X, Wang Z, et al. The canonical Wnt signaling pathway in autism[J]. CNS Neurol Disord Drug Targets, 2014,13(5):765-70.
[32]Zhang Y, Yang C, Yuan G, et al. Sulindac attenuates valproic acid-induced oxidative stress levels in primary cultured cortical neurons and ameliorates repetitive/stereotypic-like movement disorders in Wistar rats prenatally exposed to valproic acid[J]. Int J Mol Med, 2015, 35(1): 263-270.
[33]Kwan V, Unda BK, Singh KK. Wnt signaling networks in autism spectrum disorder and intellectual disability[J]. J Neurodev Disord, 2016, 8:45.
[34]Harris KP, Akbergenova Y, Cho RW, et al. Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development[J]. J Neurosci, 2016, 36(21): 5820-5832.
[35]Yi JJ, Paranjape SR, Walker MP, et al. The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome[J]. J Biol Chem, 2017, 292(30): 12503-12515.
[36]Hormozdiari F, Penn O, Borenstein E, et al. The discovery of integrated gene networks for autism and related disorders[J]. Genome Res, 2015, 25(1): 142-154.
[37]Zeidán-Chuliá F, de Oliveira BH, Salmina AB, et al. Altered expression of Alzheimer's disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy[J]. Cell Death Dis, 2014, 5: e1250.
[38]Mertz J, Tan H, Pagala V, et al. Sequential elution interactome analysis of the mind bomb 1 ubiquitin ligase reveals a novel role in dendritic spine outgrowth[J]. Mol Cell Proteomics, 2015, 14(7):1898-1910.