新型脊柱外固定技术减少医源性脊旁肌损伤的动物模型研究

doi:10.13418/j.issn.1001-165x.2021.03.012

Abstract

Abstract: Objective　To verify the advantages of spinal external fixation surgery in reducing paraspinal muscle injury.　Methods　Ten goats were randomly divided into a spinal external fixation surgery group and an open internal fixation surgery group. The experimental animals were sacrificed at 3 months after operation. The lumbar vertebrae of the surgical segment were scanned by 3.0T MRI, and the paraspinal muscle tissue was completely dissected for quasi-static tensile test and pathological section. The effects of the two surgical methods on paraspinal muscle were analyzed.　Results　The goat animal model was successfully constructed. MRI showed that compared with the open internal fixation surgery group, there were only a small amount of muscle injury around the screw in the spinal external fixation surgery group. Quasi-static tensile mechanical tests, tissue section staining (HE staining, Masson staining) all suggested that there was less muscle injury in the spinal external fixation surgery group. There are statistical differences. Conclusions　The method of spinal external fixation through percutaneous nail implantation and external orthopedic fixation was verified to reduce the paraspinal muscle injury caused by postoperative internal fixation device compression and interference.

Key words: New spinal external fixator, 　Goat paraspinal muscle, 　Surgical injury, 　Animal experiment

CLC Number:

Li Shan, Peng Wen, Yan Yiguo, Wang Cheng, Song Xizheng, Li Xuelin, Ouyang Zhihua, Xue Jingbo, Wang Wenjun. Animal experimental study of new spinal external fixation surgery on paraspinal muscle injury[J]. Chinese Journal of Clinical Anatomy, 2021, 39(3): 311-318.

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Animal experimental study of new spinal external fixation surgery on paraspinal muscle injury

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