Abstract: Objective    To explore the short-term clinical study of unilateral biportal endoscopic (UBE) technique in the treatment of adjacent segment disease (ASD) after posterior lumbar interbody fusion. Methods   The clinical data and follow-up of patients admitted to the department of spine surgery using UBE for the treatment of ASD after posterior lumbar interbody fusion from May 2020 to January 2022 were retrospectively analyzed.   Results    A total of 12 patients who met the criteria were successfully completed the surgery, and the follow-up time ranged from 16 to 36 months, with a mean of (24.3±4.6) months. Surgical time ranged from 47 min to 83 min, with a mean of (62.9±9.8) min. One case developed nerve root irritation symptoms, which were treated with hormones, dehydration and other symptomatic treatments, and the patient's symptoms were relieved after 2 days. No other complications occurred. The length of hospitalization ranged from 5 days to 10 days, with a mean of (6.9±1.6) days. At 3 days, 3 months, 6 months, 12 months and the final follow-up after surgery, the VAS score of low back pain, VAS score of lower limb pain and ODI score were significantly decreased compared with those before surgery, and the difference was statistically significant (P<0.001). At the 6-month postoperative follow-up, the excellent rate was 91.67% (11/12) as assessed by the modified MacNab criteria. In terms of imaging: complete nerve decompression was seen on review MRI at 3 days postoperatively. Review lumbar spine CT showed that the range of osteotomy of the inferior articular eminence to the articular facet distance was (3.84~6.93) mm, with an average of (5.07±1.03) mm. Isthmus bone retention preservation ranged from 4.85 mm to 7.94 mm, with an average of (5.96±0.81) mm. Lumbar spine power position was reviewed at 3 months postoperatively and at the final follow-up visit, and there was no vertebral instability and no responsible segmental recurrence.   Conclusions   Unilateral biportal endoscopic technique for treating adjacent segment disease after posterior lumbar interbody fusion is less traumatic, shorter operation time, higher patient satisfaction, and clear short-term efficacy.

Key words: Unilateral biportal endoscopic; ,  , Posterior lumbar interbody fusion; ,  , Adjacent segment disease