Abstract: Objective    To investigate the clinical effect of talonavicular-cuneiform (TNC) arthrodesis in the treatment of Müller-Weiss disease (MWD) for at least 5 years mid-term follow-up.    Methods    A total of 20 patients undergoing TNC arthrodesis for MWD were retrospectively reviewed between January 2015 and August 2018. The radiographic parameters (preoperative, three months after the operation, and final follow-up), clinical results (preoperative, two years after the operation, and final follow-up) and complications were evaluated and analyze.   Results   The mean follow up period was 72.05±8.86 months (range 60 to 93). There were significant differences in the calcaneal pitch angle (CPA), Tomeno-Meary's angle (TMA), anteroposterior (AP) Meary's angle and talonavicular coverage angle (TCA) before operation and three months after operation (P<0.05). There was no significant difference in the radiographic results between three months after the operation and the final follow-up (P>0.05). The scores of AOFAS and VAS at the final follow-up were significantly improved compared with those before and two years after the operation (P<0.05). Three patients had early complications, five had late complications, and one patient was treated with a second operation (calcaneal osteotomy). Conclusions The treatment of MWD with talonavicular-cuneiform arthrodesis combined with iliac bone autograft is effective and can be maintained until mid-term follow-up.

Key words: Muller-Weiss disease,  ,  , Talonavicular-cuneiform arthrodesis,  ,  , Iliac bone graft,  ,  , Mid-term results