Abstract: Objective    To explore the impact of using neurophysiological monitoring during spinal cord intramedullary tumor resection surgery on surgical outcomes and patient prognosis.    Methods    A retrospective study was conducted on 92 patients with spinal cord intramedullary tumors who underwent microsurgical resection treatment at Beijing Jishuitan Hospital affiliated to Capital Medical University from January 2018 to December 2020. Among them, 48 patients received traditional microsurgical resection treatment (control group), while the other 44 patients received microsurgical resection treatment + neurophysiological monitoring (combination group). The surgical resection effects, spinal cord function evaluation at different times before and after surgery, clinical symptoms and postoperative occurrence at 3 years were compared between the two groups.   Results    There was no statistical difference in total tumor resection rate between the combined group and control group (P>0.05). Before surgery, there was no statistical difference in the incidence of sensory dysfunction, motor dysfunction, pain and sphincter dysfunction between the combination group and the control group (P>0.05). The incidence of sensory dysfunction and motor dysfunction in combined group patients at 6 months and 3 months after surgery were significantly lower than those in control group (P<0.05). Before surgery, there was no statistical difference in the composition of the McCormick grading of spinal cord function between combination group and control group (P>0.05). After 6 months of postoperative evaluation, the McCormick grading of spinal cord in combination group was better than that in the control group (P<0.05). After a 3-year follow-up, the recurrence rate in combination group was 6.82%, while the recurrence rate in control group was 12.50%. There was no statistical difference in the recurrence rate between two groups (P>0.05).    Conclusions    The use of neurophysiological monitoring during spinal cord intramedullary tumor resection surgery is more conducive to reducing spinal cord injury caused by surgery, promoting postoperative recovery of motor and sensory functions and spinal cord function in patients, but it has little impact on the prognosis of patients.

Key words: Spinal cord; ,  , Intramedullary tumors; ,  , Microscopic surgery; ,  , Neuroelectrophysiological monitoring; ,  ,  Prognosis