Abstract:

Objective　 To summarize the experience in radical excision of hilar cholangiocarcinoma by regional blocking of hepatic hilum. Methods: The clinical data and long-term outcome of 49 cases of hilar cholangiocarcinoma were analyzed retrospectively, from 2002 to 2009. 24 cases (treatment team) were resected radically after anatomizing and blocking hepatic hilum. 25 cases (contrast team) were resected radically by normal way.　Results　In treatment team, 2 cases of bile leak and 2 cases of pulmonary infection were found and cured by non-operation ways. In contrast team, 2 cases of dead, 1 cases of bleeeding in hepatic cross-section, 2 cases of bile leak, 2 cases of pulmonary infection were found. 40 cases were visited. The average survival time was 26 months (2~65 months). Complications of the cases with high total bilirubin (≥300μmol/L）were higher than the lower (P<0.05）.　Conclusions　The cases with high total bilirubin(≥300 u mol/L）should be treated before operation. The best prognosis can be achieved by radical excision for patient with hepatic hilar cholangiocarcinoma. The methods of regional blocking of hepatic hilum could decrease the volume of hemorrhage, death rate and occurrence of complications after operation.

Key words: Hepatic hilum,  , Bile duct neoplasm, Regional blocking of hepatic hilum, Hepatectomy