n-HA/PA66与PEEK cage在颈前路椎间盘切除减压术后椎间隙重建的比较研究

Abstract

Abstract:

Objective　To evaluate the preliminary efficacy using polyetheretherketone cage (PEEK Cage) and Nano-hydroxyapatite polyamide/66 cage (n-HA/PA66 Cage) composites for reconstruction following anterior cervical intervertebral discectomy and fusion (ACDF) in cervical spondylosis.　Methods　We performed a retrospective study of patients (57 cases, 31cases in n-HA/PA66 group, 26 cases in PEEK group) with cervical spondylopathy who underwent ACDF by two different cages between June 2008 and June 2011. Cervical pathologies included cervial spondylotic myelopathy and cervical radiculopathy. All patients were assessed clinically and radiologically. Clinical outcome was evaluated using Odom's criteria, radiology result included subsidence of the cages, the angle of cervical lordosis, the fusion rate and interspace height.　Results　There was no significant difference of fusion rate between both groups （97.7% vs. 100% , P＞0.05 ）. As well the loss of cervical lordosis (2.06±1.77° vs. 2.39±1.56°, P=0.384). The mean loss of interspace height (0.46±0.52 mm) in n-HA/PA66 group was a little higher than that (0.41±0.18 mm) in PEEK group, without significant difference in both groups（P=0.599）. An interspace collapse of 3mm or greater was observed in 2.3% in n-HA/PA 66 cage group, compared with zero one in the PEEK group(P=0.372). The PEEK group achieved an 81% rate of successful clinical outcomes, compared with 77% in the n-HA/PA 66 group (P=0.757).　Conclusions　The n-HA/PA66 cage is as good as PEEK cage in preliminary outcomes for anterior cervical intervertebral disc discectomy and fusion.

Key words: Nano-hydroxyapatite polyamide/66(n-HA/PA 66), Polyetheretherketone (PEEK ), Cage, Anterior cervical intervertebral discectomy and fusion (ACDF)

CLC Number:

R681.53

LIU Xian-Hong, OU Yun-Sheng, JIANG Dian-Meng, QUAN Zheng-Hua, ZHANG Le, CHEN Xin, HU Zhen-Meng. Initial curative effect comparision of ano-hydroxyapatite polyamide-66 cage and polyetheretherketone cage on anterior cervical intervertebral disc discectomy and fusion[J]. Chinese Journal Of Clinical Anatomy, 2012, 30(6): 687-692.

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Initial curative effect comparision of ano-hydroxyapatite polyamide-66 cage and polyetheretherketone cage on anterior cervical intervertebral disc discectomy and fusion

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