改良阴茎海绵体压力测定方法在建立糖尿病性ED大鼠模型中的应用研究

Abstract

Abstract:

Objective　To evaluate the modified method of intracavernous pressure(ICP) monitoring in establishing rat model with diabetic erectile dysfunction.　Methods　Forty male rats were randomized equally into 2 groups (control group and diabetic group). ICP and arterial pressure (AP) were monitored with the improved method and the traditional method, respectively. The modified method used improved intravenous infusion needle puncture in the crus of penis. Results There was no significant difference in measurement of the ICP and AP between the modified method and the traditional method（P＞0.05）, both in the control group and diabetic group. The modified method used improved intravenous infusion needle puncture in the crus of penis can improve the success rate significantly (the traditional method being 75% and the modified method being 100%).　Conclusion　The modified method of intracavernous pressure monitoring has characteristic of stable、accurate、higher success rate. It is of great significance for establishing rat model with diabetic erectile dysfunction and evaluating rat penile erectile function.

Key words: Modification, Intracavernous pressure, Method, Erectile dysfunction, Diabetic

CLC Number:

R698

TUN Zi-Yun, HE Shu-Hua, ZHANG Chao, LIU Lu-Gao, HUI An-Yang. Research for modification of intracavernous pressure monitoring in establishing rat model with diabetic erectile dysfunction[J]. Chinese Journal Of Clinical Anatomy, 2013, 31(2): 192-195.

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Research for modification of intracavernous pressure monitoring in establishing rat model with diabetic erectile dysfunction

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