Chinese Journal Of Clinical Anatomy ›› 2013, Vol. 31 ›› Issue (3): 279-282.

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Applied anatomic study about the central retinal artery in SD rats

WAN Wei 1,2, LIU Zheng-hai2, WU Xiao-qiong1, WANG Xiao-sheng1, LUO Xue-gang1   

  1. 1.Department of Human Anatomy and Neurobiology, Xiangya Medical College of Central South University, Changsha 410013, China;2.Department of Human Anatomy, University of South China, Hengyang 421001, China
  • Received:2013-01-20 Online:2013-05-25 Published:2013-06-06

Abstract:

Objective To provide anatomical basis for establishment of a reliable animal model of optic nerve injury.    Method    Red latex perfusion technology was used to observe the origin, course, distribution of central retinal artery, and its relationship with the optic nerve in normal SD rats and measurement about several parameters was made on the micrographs recorded using the stereoscopic microscope; Moreover, gelatin-ink perfusion technique was adopted to demonstrate the blood supply of the retina with the optic nerve transected at 2.0 mm and 6.0 mm posterior to the posterior pole of the eye.     Result    Our study shown the central retinal artery and its branches run with the optic nerve at its course within the optic nerve sheath; the origin of the central retinal artery was located (5.784±0.054) mm posterior to the posterior pole of the eye; the vascular density of the central retinal nerve is highest at the sectional surface of it 6.0 mm posteior to the posterior role of the eye.   Conclusion   In the preparation of the SD rats model with nerve injury, transection should be made within the sheath, with the best place of the transection being located 6.0 mm posterior to the posterior pole of the eye.

Key words: SD rat, Central retina artery, Gelatin ink, Latex

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