颈内动脉狭窄对大脑动脉环血流动力学影响的有限元分析

doi:10.13418/j.issn.1001-165x.2016.06.015

Abstract

Abstract:

Objective　The cerebral arterial circle is usually associated with the internal carotid artery (ICA) stenosis. The finite element method was used to analyze the influence of stenosis on the hemodynamics in the circle and find out the compensatory mechanism of communicating arteries.　Methods A fluid-solid coupling 3D finite element model was created using MIMICS10.0 and ANSYS14.5. The healthy and the diseased (ratios of stenosis include 15%, 30%, 45%, 60%, 70%, 80%, and 90%) situations were simulated. Blood flow was then monitored at the communicating arteries (ACoA,PCoA).　Results　A fluid-solid coupling 3D finite element model including blood and vessels was created for the first time. Blood flow in ACoA and the right PCoA increased according to the increase of stenosis ratio, but decreased when the stenosis ratio was up to 90%. Blood flow in the left PCoA increased slightly through the whole course. Conclusion　The ACoA and PCoA of affected side open gradually to compensate the loss of blood according to the increasing of stenosis ration, and decompensate when the rate was up to 90%. Stenosis in the internal carotid was proved mechanical associate with intracranial ischemic disease.

Key words: Cerebral arterial circle, Carotid Stenosis, Finite Element Analysis

LIN Wei-shen, ZHOU Yi-qiang, HUANG Xue-cheng, LI Yi-kai. Hemodynaic of cerebral arterial circle affected by stenosis in ICA: A finite element analysis[J]. Chinese Journal Of Clinical Anatomy, 2016, 34(6): 672-676.

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Hemodynaic of cerebral arterial circle affected by stenosis in ICA: A finite element analysis

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