Abstract: Objective　To retrospectively analyze the effect of erector spinae plane block and serratus anterior plane block on acute pain after single-port thoracoscopic surgery.    Methods　Eighty-seven patients were selected, who underwent selective thoracoscopic surgery under total intravenous general anesthesia in our hospital from January to December 2018. Twenty-nine patients who only accepted total intravenous general anesthesia were assigned to the control group. The 30 patients who accepted total intravenous general anesthesia (TIVA) combined with erector spinae plane block (ESPB) were assigned to the ESPB group. Twenty-eight patients who accepted TIVA combined with serratus anterior plane block (SAPB) were assigned to SAPB group. All patients accepted patient controlled intravenous analgesia (PCIA) for postoperative analgesia. Heart rate, blood pressure, and pulse oximetry were routinely monitored during anesthesia. VAS scores were obtained before surgery, 2 h, 8 h, 12 h, 24 h, and 48 h after surgery. Opioids consumption during the operation and PCIA were also recorded. Additionally, postoperative complications such as nausea and vomiting, urinary retention, itching and respiratory depression during 48 h after surgery were also recorded.  Results　VAS scores in the ESPB and SAPB group were significantly lower than those in the control group at 2, 8 and 12 h postoperatively. And the ESPB group was lower than SAPB group (P<0.05). Compared with the control group, the opioids consumption during the operation and PCIA of ESPB and SAPB group were significantly decreased and the ESPB group decreased more than the SAPB group (P<0.05).　Conclusion　In the perioperative analgesia of thoracoscopic surgery, ultrasound-guided ESPB has better analgesic effect than SAPB, reducing perioperative opioid consumption. 

Key words:  , Erector spinae, 　Serratus anterior, 　Nerve block, 　Pain