87例慢性阻塞性肺疾病患者上下肢肌力等速测试分析

doi:10.13418/j.issn.1001-165x.2019.06.021

Abstract

Abstract: Objective　To analyze the muscle strength of upper and lower limbs in patients with chronic obstructive pulmonary disease (COPD) by using isokinetic testing.　Methods　The flexors and extensors of the elbow and knee in 87 patients with COPD (experimental group, mild 17, moderate 44, severe 26) and those in 34 healthy subjects (control group) were assessed by using isokinetic testing. The flexion and extension muscle peak torque (PT) of elbow and knee at angular velocity 60°/s and 180°/s were recorded respectively. The fatigue index of lower limb flexor and extensor muscles was also calculated respectively. Results　The muscle PT of elbow flexion and extension in experimental group were (20.56±7.54) Nm and (22.61±9.26) Nm respectively, the muscle PT of knee flexion and extension in experimental group were (35.78±16.99) Nm and (71.86±27.98) Nm respectively, which were lower than those of in the control group (P<0.05). The fatigue index of lower limb flexor and extensor muscles in experimental group was lower than that of in the control group (P<0.05).　Conclusions　Isokinetic muscle testing can be used as a method to analyze the changes of peripheral muscle strength in patients with COPD.

Key words: Chronic obstructive pulmonary disease, 　Isokinetic muscle testing, 　 Peak torque

CLC Number:

R563
R496

BAI Li-ming, ZHANG Lei, ZHANG Ming-sheng. Analysis of upper and lower limbs muscle strength in 87 patients with chronic obstructive pulmonary disease by using isokinetic testing[J]. Chinese Journal of Clinical Anatomy, 2019, 37(6): 718-720.

References 12

[1]	Choudhury G, Rabinovich R, MacNee W. Comorbidities and systemic effects of chronic obstructive pulmonary disease[J]. Clin Chest Med, 2014, 35(1): 101-130.
[2]	Kevin Gruffydd-Jones. GOLD guidelines 2011: what are the implications for primary care[J]. Prim Care Respir J, 2012, 21(4): 437-441.
[3]	Ribeiro F, Lépine PA, Garceau-Bolduc C, et al. Test-retest reliability of lower limb isokinetic endurance in COPD: a comparison of angular velocities[J]. Int J Chron Obstruct Pulmon Dis, 2015, 10(6): 1163-1172.
[4]	Miranda EF, Malaguti C , Marchetti PH, et al. Upper and lower limb muscles in patients with COPD: similarities in muscle efficiency but differences in fatigue resistance[J]. Respir Care, 2014, 59 (1): 62-69.
[5]	Hopkinson NS, Tennant RC, Dayer MJ, et al. A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease[J]. Respir Res, 2007, 8(1): 25.
[6]	Vivodtzev I, Flore P, Lévy P, et al. Voluntary activation during knee extensions in severely deconditioned patients with chronic obstructive pulmonary disease: benefit of endurance training[J]. Muscle Nerve, 2008, 37(1): 27-35.
[7]	Seymour JM, Spruit MA, Hopkinson NS, et al. The prevalence of quadriceps weakness in COPD and the relationship with disease severity[J]. Eur Respir J, 2010, 36(1): 81-88.
[8]	Caron MA, Debigaré R, Dekhuijzen PN, et al. Comparative assessment of the quadriceps and the diaphragm in patients with COPD[J]. J Appl Physiol, 2009, 107(3): 952-961.
[9]	Menon MK, Houchen L, Singh SJ, et al. Inflammatory and satellite cells in the quadriceps of patients with COPD and response to resistance training[J]. Chest, 2012, 142(5): 1134-1142.
[10]	Robles PG, Sussman MS, Naraghi A, et al. Intramuscular fat infiltration contributes to impaired muscle function in COPD[J]. Med Sci Sports Exerc, 2015, 47(7): 1334-1341.
[11]	Butcher SJ, Lagerquist O, Marciniuk DD, et al. Relationship between ventilatory constraint and muscle fatigue during exercise in COPD[J]. Eur Respir J, 2009, 33(4): 763-770.
[12]	van den Borst B, Slot IG, Hellwig VA, et al. Loss of quadriceps muscle oxidative phenotype and decreased endurance in patients with mild-to-moderate COPD[J]. J Appl Physiol (1985), 2013, 114(9): 1319-1328.

Analysis of upper and lower limbs muscle strength in 87 patients with chronic obstructive pulmonary disease by using isokinetic testing

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