Abstract: Objective　To explore the clinical efficacy of the first metatarsal proximal perforator-based neurocutaneous vascular flap for repairing the forefoot soft-tissue defects.　Methods　From March 2014 to November 2019, eight patients with forefoot defects were reconstructed by the first metatarsal proximal perforator-based neurocutaneous vascular flaps with an average size from 6.0 cm×4.9 cm to 3.0 cm×2.1 cm.　Results　All flaps survived completely and the donor sites healed uneventfully. After a follow-up of 3 to 12 months, the flaps presented an excellent texture, a fine elasticity, and a similar skin color. And the patients were satisfied with both the functions and appearances of the donor and recipient regions.　Conclusions　Due to the good and reliable blood supply and the simple and practical surgical procedure, the first metatarsal proximal perforator-based neurocutaneous vascular flap might become a new choice for the repair of forefoot soft-tissue defects.

Key words: Foot, 　Neurocutaneous vascular flap；　The first metatarsal proximal perforator；　Injury