Abstract: Objective　To investigate the clinical application of individualized skin flap in the treatment of contracture of first web space by 3D printing the model of the affected hand.　Methods　From March 2018 to October 2019, 10 cases of moderate and severe contracture of first web space were treated with 3D printing of the affected hand model before operation. The appropriate flaps were selected to repair the wound individualized according to the shape and area of the wound after opening the first web space of the model. Intraoperative comparison and verification, postoperative follow-up were performed to observe the treatment effect.　Results　The shape and area of the wound and the flap selection were basically in accordance with that of the preoperative simulation design. All the 10 cases of flaps survived, and the donor and recipient wound were healed at I stage.  All flaps were followed up for 6~12 months. The appearance of the flaps was satisfactory, the sensation was partial recovered the abduction and opposition function of the thumb were restored. The angle of first web space increased by 50°-60°(with an average of 53.4°), and the width increased by 18mm-35 mm (with an average of 31.3 mm). The repair evaluation of the first web space were excellent in 7 cases, good in 2 cases, medium in1 case.　Conclusions　The 3D printing of the affected hand model before operation can guide the individualized skin flap, so that the enlarged wound with contracture can be repaired accurately, the operation time can be reduced, and the shape and function of the first web space can be recovered well after operation.

Key words: 3D printing, 　Contracture of the first web space, 　Flap, 　 Individualized