富血小板血浆联合钻孔减压、同种异体腓骨支撑治疗早期股骨头坏死的研究

doi:10.13418/j.issn.1001-165x.2018.01.021

Abstract

Abstract:

Objective　To investigate the potency of the platelet-rich plasma (PRP) combined with core decompression and allogeneic fibula rod support for the treatment of the osteonecrosis of the femoral head.　Methods　From July 2014 to May 2017, 26 cases (35 hips) of osteonecrosis of the femoral head were treated with platelet-rich plasma combined with core decompression and allogeneic fibula rod support (PRP group) and 24 cases (32 hips) with core decompression and allogeneic fibula rod support only (control group). At 1, 3，6 months after operation, Patients were followed up and evaluated using Harris hip score、VAS score and radiography.　Results　All the patients(67 hips) were followed up thoroughly and the follow-up periods were 6 months. At 6 months after operation, the shape of the femoral heads of the PRP groups was good with no deformation and collapse. The location of the top of the allograft fibula rod was perfect with no fibula rod out. The fibula rods made integration with the surrounding bone without infection. Harris score of PRP group before and after treatment increased from 67.82±9.61 to 88.45±6.02, Harris score of control group before and after treatment increased from 69.74±8.26 to 78.36±6.17；VAS score of PRP group before and after treatment increased from 4.6±1.2 to 1.7±1.0, VAS score of control group before and after treatment increased from 4.3±0.9 to 2.3±1.1. There were statistically significant differences in the pre-therapy and post-treatment groups (P<0.05) and there were statistically significant differences in the postoperation between the two groups (P<0.05).　Conclusions　Use of the platelet-rich plasma (PRP) in clinic can ease hip pain and improve joint function, and it is highly valuable in clinical use．

Key words: Platelet-rich plasma, 　Osteonecrosis of the femoral head, 　 Allogeneic fibula rod, 　Core decompression

JIANG Liang-bin,LIU Song, YUE Yong-bin, SUN Hai-zhong，WEI Biao-fang. Early research of the platelet-rich plasma (PRP) combined with core decompression and allogeneic fibula rod support for the treatment of the osteonecrosis of the femoral head[J]. Chinese Journal Of Clinical Anatomy, 2018, 36(1): 93-97.

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Early research of the platelet-rich plasma (PRP) combined with core decompression and allogeneic fibula rod support for the treatment of the osteonecrosis of the femoral head

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