Abstract: Objective　To explore how to use PeriCam PSI blood perfusion speckle imager to detect the blood perfusion in tongues of cynomolgus monkey subjects and analyze its feasibility and application values.　Methods　1. Five female cynomolgus monkeys were subjected to cervical cerclage in preparation for their endometriosis (EMs) models. One of them only served as an indicator of pelvic conditions after its laparotomy. 2. PeriCam PSI blood flow perfusion speckle imager was used to measure the blood perfusion on the surfaces and bases of tongues of all cynomolgus monkeys for their preoperative conditions, in the very month of the coming surgery, and s.p. 1th, 2nd and 3rd months respectively. PIMSoft, the matched software, was used in data collection and analysis.　Results　1. Blood perfusion volume on tongues of the 6 subjects at different phases was successfully captured and five out of them s.p. cervical cerclage were seen to undergo significant ups/downs of their blood perfusion volume with statistical significance in their discrepancy. 2. The blood perfusion volume of tongue surfaces and bases of cynomolgus monkeys with s.p. 2 months mild-moderate pelvic adhesion was significantly higher than that of non-adhesion counterparts, the difference being statistically significant.　Conclusions　The method of PeriCam PSI blood perfusion speckle imager to detect the blood perfusion in tongues of cynomolgus monkey subjects is stably feasible and might be incorporated in one of the quantitative evaluation methods for modeled tongue pictures based on diseases-symptoms.

Key words: PeriCam PSI blood perfusion speckle imager, 　Tongue pictures, 　Blood perfusion volume；　Cynomolgus monkey model；　Animal surgery