颗粒植骨，钛网植骨和髂骨植骨在后入路单节段腰椎结核病灶清除术中的疗效研究

doi:10.13418/j.issn.1001-165x.2022.2.16

Abstract

Abstract: Objective　To compare the clinical outcomes of iliac bone graft, titanium mesh bone graft and granular bone graft in the surgical treatment of single segment lumbar tuberculosis.　Methods　A retrospective analysis was performed on 98 patients who underwent one stage posterior debridement, bone graft and internal fixation for single segment lumbar tuberculosis from July 2015 to September 2020, involving 32 case in autologous iliac bone graft group, 32 case in titanium mesh bone graft group and 34 cases in granular bone graft group. The operative time, intraoperative blood loss, postoperative hospital stay, visual analogue scale (VAS) score, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ASIA grade, Cobb angle correction and loss, and bone graft fusion time were recorded and analyzed.　Results　The average follow-up time was 28 months (14~53 months). The operation time and bone graft fusion time in the granular group were (192.6±42.1) min, (5.2±1.1) months, which were better than those in the iliac bone group (229.2±61.6) min, (8.0±2.9) months and titanium mesh group (233±51.5) min, (8.6±5.6) months (P<0.05). The amount of intraoperative blood loss in the granular group (385.3±251.8) mL was less than that in the titanium mesh group (660.9±486.4) mL (P<0.05), but there was no significant difference in the amount of intraoperative blood loss between the granular group and the iliac bone group (534.4±395.4) mL, (P=0.122). After operation, the Cobb angle of lumbar segmental kyphosis significantly improved in the three groups at the last follow-up, but there was no significant difference in loss and correction of Cobb angle among the three groups (P>0.05). There were no statistical difference in the other indicators among the three groups.　Conclusions　Compared with iliac bone graft and titanium mesh bone graft, granular bone graft has the advantages of simple and feasible operation, shorter operation time, less blood loss and faster postoperative bone graft fusion. It is a safe and effective bone graft method for single segmental lumbar tuberculosis via posterior approach.

Key words: Lumbar tuberculosis, 　Posterior approach, 　Internal fixation, 　Bone graft fusion methods

CLC Number:

R687

Jiang Guanyin, Ou Yunsheng, Zhu Yong, Luo Wei, Du Xing, Zhang Wei, Qin Wanyuan. Study on the curative effects of granular bone graft, titanium mesh bone graft and iliac bone graft in single-segment lumbar tuberculosis focus debridement by posterior approach[J]. Chinese Journal of Clinical Anatomy, 2022, 40(2): 204-210.

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Study on the curative effects of granular bone graft, titanium mesh bone graft and iliac bone graft in single-segment lumbar tuberculosis focus debridement by posterior approach

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