肺癌术后肺复张形态与肺功能相关性及其影响因素的研究

doi:10.13418/j.issn.1001-165x.2022.5.19

Abstract

Abstract: Objective To analyze lung re-expansion and pulmonary function and their influencing factors by using quantitative CT and a spirometer. Methods A single-center retrospective study including post-operation patients with lung cancer was conducted. Quantitative CT was used to calculate the lung volume before operation and 3 months after operation. Respiratory function indicators including FVC, FEV1 and FEV1/FVC were estimated by a spirometer. The correlation between lung volume and pulmonary function was analyzed. According to the pulmonary expansion indicator, the patients were divided into a non-distention group and hyperdistention group. The changes of lung volume and pulmonary function before and after operation were compared. Results A total of 40 patients were included in this study. Both lung volume and pulmonary function decreased after operation. The preoperative FVC (r=0.36, P=0.037) and FEV1 (r=0.35, P=0.041) were positively correlated with lung volume, and there was no significant correlation between FVC, FEV1 and lung volume at 3 months after operation (P>0.05). Compared with the non-distension group, the preoperative FEV1/FVC of patients in the hyperdistention group was lower, and the FEV1/FVC improved by about 5% at 3 months after operation. Univariate analysis revealed that smoking history was more common in the hyperdistention group (P=0.045). Conclusions Quantitative CT measurements combined with pulmonary function tests can be used to identify early postoperative lung hyperdistention morphology. Smoking history is a predictor of postoperative hyperdistention in patients with lung cancer.

Key words: Quantitative CT; , , Lung volume; , , Pulmonary function; , , Lung expansion; , , Factors

CLC Number:

R323

Li Xinping, Chen Yi, Liu Shuangchun, Zeng Bin, Zhang Mingsheng. Correlation between lung re-expansion and pulmonary function and its influencing factors after lung cancer operation[J]. Chinese Journal of Clinical Anatomy, 2022, 40(5): 610-614.

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Correlation between lung re-expansion and pulmonary function and its influencing factors after lung cancer operation

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