同型半胱氨酸测定在急性脑梗塞合并颈动脉病变的临床应用价值分析

doi:10.13418/j.issn.1001-165x.2017.06.022

Chinese Journal Of Clinical Anatomy ›› 2017, Vol. 35 ›› Issue (6): 695-699.doi: 10.13418/j.issn.1001-165x.2017.06.022

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The clinical value of homocysteine in acute cerebral infarction with carotid artery lesions

YIN Wen-ming, YAO Yi-qin, ZOU Rong-cheng

Department of Neurology, Lishui District People's Hospital, Nanjing 211200, China

Received:2017-07-10 Online:2017-11-25 Published:2017-12-30

Abstract

Abstract:

Objective　The purpose of this study was to investigate the correlation between homocysteine levels and carotid artery lesion in acute cerebral infarction. 　Methods 　A total of 215 patients with clinically diagnosed acute cerebral infarction were divided into two groups, the high Hcy group (n=103) and the low Hcy group (n=112).　Results　Plaques and severe arterial stenosis are more likely to occur in high Hcy group. The level of plasma Hcy positively correlated to the number of plaque and soft plaque (Kendall correlation coefficient=0.145, P=0.006<0.05); the relation between plasma Hcy levels and the incidence of severe arterial stenosis was positive (Kendall correlation coefficient=0.359, P=0.000<0.05).　Conclusion　Plasma Hcy levels in the patients with acute cerebral infarction were positively correlated with the incidence of carotid plaques and stenosis, suggesting active intervention of hyperhomocysteinemia might be of help for the prevention of carotid artery plaques and stenosis.

Key words: Acute cerebral infarction, 　Plasmic homocysteine;　Carotid artery lesions

YIN Wen-ming, YAO Yi-qin, ZOU Rong-cheng . The clinical value of homocysteine in acute cerebral infarction with carotid artery lesions[J]. Chinese Journal Of Clinical Anatomy, 2017, 35(6): 695-699.

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The clinical value of homocysteine in acute cerebral infarction with carotid artery lesions

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